Saxenda
What is Saxenda?
At Manchester Weight Loss Clinics, we are committed to delivering medically supervised, evidence-based weight management solutions. Saxenda (liraglutide 3 mg) is one such option available by private prescription, used to support weight loss and long-term weight control in adults with obesity or overweight and related health risks. Saxenda is the brand name for liraglutide 3 mg, a glucagon-like peptide-1 (GLP-1) receptor agonist. It is a once-daily injectable medication licensed in the UK for weight management. This treatment should be used in conjunction with a reduced-calorie diet and increased physical activity.
Please note that this medication may only be prescribed following a full medical consultation by a qualified prescriber, in line with UK legislation and professional standards set by the General Pharmaceutical Council (GPhC).
How Does Saxenda Work?
Saxenda contains liraglutide, a synthetic analogue of the GLP-1 hormone, which helps regulate appetite and energy balance. By binding to and activating GLP-1 receptors, it works through several mechanisms:
- Increases satiety (feeling of fullness) and reduces hunger signals
- Slows gastric emptying, delaying the return of hunger after eating
- Reduces food intake, helping to establish a calorie deficit
Although liraglutide is also licensed at lower doses for managing type 2 diabetes (under the brand name Victoza), the 3 mg dose in Saxenda is specifically indicated for weight management.
Clinical Efficacy
Saxenda’s efficacy has been demonstrated in several large-scale clinical trials, including the SCALE programme, which assessed its impact in both diabetic and non-diabetic populations.
Key Findings from the SCALE Obesity and Prediabetes Trial:
- Patients receiving Saxenda (alongside lifestyle changes) lost an average of 8% of their body weight over 56 weeks, compared to 2.6% in the placebo group.
- 63% of participants on Saxenda lost ≥5% of their body weight
- 33% achieved ≥10% weight loss
These results are considered clinically meaningful and were associated with improvements in:
- Waist circumference
- Blood pressure
- Fasting glucose and lipid profiles
Access and Pricing
Saxenda is offered at Manchester Weight Loss Clinics via private prescription only. Access is based on:
- Meeting the BMI and clinical criteria
- Undergoing a medical assessment by a qualified prescriber
- Commitment to a supervised weight loss programme
Treatment cost varies depending on duration, dosing, and patient-specific requirements. All medication is supplied with guidance on administration, safety, and lifestyle support.
